Blindness during Streptomycin and Chloramphenicol Therapy.

ALTHOUGH the toxic effects of streptomycin on the eighth nerve are well known, it is perhaps not so widely appreciated that loss of vision may complicate the administration both of streptomycin and of chloramphenicol. A patient is described who became partially blind during combined streptomycin and chloramphenicol therapy and in whom streptomycin was at first considered to be the toxic agent. However, from a review of the world literature, it is evident that either drug may be incriminated.